RESUMO
The aim of this investigation was to study the effects of clenbuterol treatment (1 mug/kg b.w. i.m. for 10 consecutive days) on haemocoagulation process in seven calves. From each animal, blood samples were taken before (basal sample) and 24, 72, 144, 216, 264, 336 and 360 h after the end of treatment and some parameters were evaluated: coagulation process [prothrombin (PTT) and thrombin times (PT)], a complete blood count and plasmatic levels of 3'5'-monophosphatocyclic-adenosine (c-AMP) . A comparison of the values in each time group during the whole course of the experiments shows a significant increase (P < 0.03, P < 0.01) in PT and PTT at 72, 144, 216 and 264 h. Significant increase (P < 0.01) in c-AMP plasma levels were observed at 144, 216 and 264 h. All these values returned to normal levels after 360 h.
Assuntos
Agonistas Adrenérgicos beta/farmacologia , Coagulação Sanguínea/efeitos dos fármacos , Bovinos/fisiologia , Clembuterol/farmacologia , AMP Cíclico/sangue , Animais , Coagulação Sanguínea/fisiologia , Injeções Intramusculares/veterinária , Contagem de Plaquetas/veterinária , Tempo de Protrombina/veterinária , Tempo de Trombina/veterinária , Fatores de TempoAssuntos
Borrelia burgdorferi , Doenças do Cão/microbiologia , Doença de Lyme/veterinária , Animais , Infecções por Borrelia/diagnóstico , Infecções por Borrelia/transmissão , Infecções por Borrelia/veterinária , Doenças do Cão/diagnóstico , Doenças do Cão/transmissão , Cães , Feminino , Ixodes/crescimento & desenvolvimento , Ixodes/virologia , Estágios do Ciclo de Vida , Doença de Lyme/diagnóstico , Doença de Lyme/transmissão , Infestações por Carrapato/transmissão , Infestações por Carrapato/veterináriaRESUMO
The Authors describe chronic vaginitis of bovines in intensive breeding. All of the 78 subjects examined presented vaginitis, accompanied by fibrinous hydrocele. On the spermatic cord and the tail of epididymis, initial lesions consisted of granulomas and fibrinous bridges between vaginalis propria of testicle and of epididymis. Subsequently appeared adherence and synechiae, which join the deferens and epididymis body to didymis, and thickening of albuginea. Synechiae can develop between peritesticular vaginalis propria and communis. Histopathological findings: peritoneal-like papillary structures with metaplastic mesothelial cells; diffuse lympho-plasmacellular infiltration with eosinophils and mast cells; intense capillary angiogenesis. The epididymal lesions are: diffuse mononuclear infiltration; periarteritis nodosa; papillary proliferations of endothelium; endothelial degeneration; tubular ectasia and stenosis; intraepithelial cyst. Noticeable within testis: periarteritis nodosa; fibrosis of albuginea; spermatocytes vacuolisation; multinucleate spermatids; epithelial shedding. The Authors pointed out: the serological and bacteriological testings furnished inconclusive results; only pathological finding always present is a large infestation of cremasteric muscle with Sarcocystis, to which is attributed the etiopathogenesis of flogosis, that is chronic from the beginning. The Authors propose the terminology of "Chronic peritesticular and periepididymal vaginitis" or "Chronic Periorchitis and periepididymitis".
Assuntos
Doenças dos Bovinos/patologia , Epididimite/veterinária , Orquite/veterinária , Animais , Bovinos , Doença Crônica , Epididimite/patologia , Masculino , Orquite/patologiaRESUMO
In gonadectomized and totally or partially criptorchid rats, subcutaneous inoculation of 0,5 mg of DMBA often determines the development of sarcomas at variable, sometimes marked, distances from the site of inoculation. The phenomenon is exhibited maximally in rats subjected to unilateral cryptorchidism or to unilateral gonadectomy; in minimal measure in those subjected to bilateral gonadectomy. It is not exhibited in the intact animals. The Authors, though presenting several hypotheses, are not able to furnish a satisfactory explanation of the phenomenon.
